Description

2-Amino-3-(4-Chloro-1H-Indol-3-Yl)Propanoic Acid is a specialized indole derivative and a halogenated tryptophan analog with significant research and development potential. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, particularly for the development of novel pharmaceuticals and bioactive molecules. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and life science sectors who require high-purity, structurally complex intermediates for drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Biochemical Research: Used as a modified amino acid in peptide synthesis and as a probe to study enzyme-substrate interactions and receptor binding.
• Agrochemical Development: Serves as a precursor in the synthesis of advanced crop protection agents and plant growth regulators.
• Organic Synthesis Building Block: Employed in the construction of complex heterocyclic compounds and natural product analogs due to its reactive indole and amino acid functionalities.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	2-Amino-3-(4-Chloro-1H-Indol-3-Yl)Propanoic Acid
CAS No.	118244-93-2
Molecular Formula	C11H11ClN2O2
Molecular Weight	238.67 g/mol
Synonyms	4-Chloro-DL-tryptophan; (RS)-2-Amino-3-(4-chloro-1H-indol-3-yl)propanoic acid; 4-Chlorotryptophan; DL-4-Chlorotryptophan; 3-(4-Chloro-1H-indol-3-yl)-DL-alanine; 4-Cl-Trp; 4-Chloroindole-3-alanine; 2-Azaniumyl-3-(4-chloro-1H-indol-3-yl)propanoate
EINECS	Contact for details

Quality Control

Our 2-Amino-3-(4-Chloro-1H-Indol-3-Yl)Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material is suitable for demanding applications in research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.