Description

5-Amino-2-Methyl-3,4-Dihydroisoquinolin-1(2H)-One is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound is a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals, offering a unique scaffold for medicinal chemistry research. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new therapeutic agents and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex molecules for drug discovery and development, particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Serves as a privileged scaffold for constructing libraries of novel compounds in high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Fine Chemical Production: Acts as a building block for synthesizing dyes, pigments, and other specialty chemicals requiring specific amino-isoquinoline motifs.
• Academic & Industrial R&D: Employed in universities and corporate R&D labs for methodological development and exploring new chemical reactions.

Basic Information

Product Name	5-Amino-2-Methyl-3,4-Dihydroisoquinolin-1(2H)-One
CAS No.	118206-31-8
Molecular Formula	C10H12N2O
Molecular Weight	176.22 g/mol
Synonyms	5-Amino-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-one; 2-Methyl-5-amino-3,4-dihydro-1(2H)-isoquinolinone; 5-Amino-2-methyl-3,4-dihydro-1H-isoquinolin-1-one; 5-Amino-2-methyl-1,2,3,4-tetrahydroisoquinoline-1-one; 2-Methyl-5-amino-1-oxo-1,2,3,4-tetrahydroisoquinoline; 1(2H)-Isoquinolinone, 5-amino-2-methyl-3,4-dihydro-
EINECS	Contact for details

Quality Control

Our 5-Amino-2-Methyl-3,4-Dihydroisoquinolin-1(2H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for research and production. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.