Description

4-Acetamido-4'-Maleimidylstilbene-2,2'-Disulfonic Acid is a specialized, high-purity chemical building block designed for advanced research and development. This compound matters for its unique bifunctional structure, which combines a maleimide group for thiol-specific conjugation with a stilbene-derived fluorescent scaffold, enabling precise labeling and tracking in complex systems. It is primarily needed by researchers and formulators in the fields of bioconjugation, fluorescent probe development, and advanced material science.

Application

• Bioconjugation Reagent: Used for site-specific labeling of proteins, antibodies, and peptides via the maleimide-thiol chemistry.
• Fluorescent Probe Synthesis: Serves as a key intermediate in creating sensitive fluorescent tags and sensors for biological imaging.
• Biomolecular Assay Development: Employed in the design of fluorescence resonance energy transfer (FRET)-based assays and diagnostic kits.
• Polymer & Material Functionalization: Used to introduce fluorescent and reactive sites onto polymers, nanoparticles, and surfaces.
• Pharmaceutical Research: Applied in drug discovery for labeling drug candidates to study their distribution and metabolism.
• Academic & Industrial R&D: A critical tool for fundamental research in chemical biology, photochemistry, and supramolecular chemistry.

Basic Information

Product Name	4-Acetamido-4'-Maleimidylstilbene-2,2'-Disulfonic Acid
CAS No.	118121-38-3
Molecular Formula	C21H16N2O9S2
Molecular Weight	504.49 g/mol
Synonyms	4-Acetamido-4'-maleimidostilbene-2,2'-disulfonic acid; AMSDS; 4-Acetamido-4'-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)stilbene-2,2'-disulfonic acid; 1-[4-[2-(4-Acetamido-2-sulfonatophenyl)ethenyl]-2-sulfonatophenyl]-1H-pyrrole-2,5-dione; Maleimide-stilbene fluorescent probe; Fluorescent maleimide derivative; Stilbene disulfonic acid maleimide
EINECS	Contact for details

Quality Control

Our 4-Acetamido-4'-Maleimidylstilbene-2,2'-Disulfonic Acid is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture and light. For long-term storage, consider desiccants and inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.