Description

4-(6-Chloroimidazo[1,2-A]Pyridin-2-Yl)Benzonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its fused imidazopyridine core and benzonitrile moiety. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with targeted biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) for investigational drugs.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Kinase Inhibitor Development: Serves as a building block for compounds targeting specific protein kinases, a major focus in oncology research.
• Chemical Biology Probes: Utilized in the creation of molecular probes to study biological pathways and protein function.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical R&D and scale-up activities.
• Academic Research: Employed in university and institutional labs for fundamental research in heterocyclic chemistry and drug design.

Basic Information

Product Name	4-(6-Chloroimidazo[1,2-A]Pyridin-2-Yl)Benzonitrile
CAS No.	118000-64-9
Molecular Formula	C14H8ClN3
Molecular Weight	253.69 g/mol
Synonyms	4-(6-Chloroimidazo[1,2-a]pyridin-2-yl)benzonitrile; 2-(4-Cyanophenyl)-6-chloroimidazo[1,2-a]pyridine; 6-Chloro-2-(4-cyanophenyl)imidazo[1,2-a]pyridine; 118000-64-9; 4-(6-Chloro-imidazo[1,2-a]pyridin-2-yl)-benzonitrile; 4-(6-Chloroimidazo[1,2-a]pyridin-2-yl)benzonitrile; 4-(6-chloroimidazo[1,2-a]pyridin-2-yl)benzonitrile
EINECS	Contact for details

Quality Control

Our 4-(6-Chloroimidazo[1,2-A]Pyridin-2-Yl)Benzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.