Description

1-(Thiophene-2-Carbonyl)-Pyrrolidine-2-Carboxylic Acid is a high-purity, heterocyclic organic compound featuring a thiophene and a proline-derived carboxylic acid moiety. This unique structure makes it a valuable advanced pharmaceutical intermediate and a versatile building block in medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Building Block: Used for structure-activity relationship (SAR) studies and library synthesis due to its constrained pyrrolidine ring and thiophene heterocycle.
• Agrochemical Research: Serves as a precursor in the development of new pesticides and herbicides, leveraging its heterocyclic framework.
• Chemical Synthesis Reagent: Employed in organic synthesis for the construction of complex molecules, including peptidomimetics and other bioactive compounds.
• Academic & Institutional Research: Used in universities and research institutes for fundamental studies in organic chemistry and drug discovery projects.

Basic Information

Product Name	1-(Thiophene-2-Carbonyl)-Pyrrolidine-2-Carboxylic Acid
CAS No.	117918-58-8
Molecular Formula	C10H11NO3S
Molecular Weight	225.26 g/mol
Synonyms	1-(Thiophene-2-carbonyl)pyrrolidine-2-carboxylic acid; 2-Pyrrolidinecarboxylic acid, 1-(2-thienylcarbonyl)-; 1-(2-Thienylcarbonyl)-2-pyrrolidinecarboxylic acid; 1-(Thiophene-2-carbonyl)-L-proline (if applicable to stereochemistry); T2CPCA; Thiophene-2-carbonyl-proline; Proline thiophene carboxamide derivative
EINECS	Contact for details

Quality Control

Our 1-(Thiophene-2-Carbonyl)-Pyrrolidine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.