Description

7-γ-(β-Hydroxypropyl)Theophylline 2',4'-Dichlorobenzoate is a high-purity, synthetic chemical intermediate derived from theophylline, characterized by its specific esterification with a dichlorobenzoic acid derivative. This compound matters for its role as a key building block in the research and development of novel pharmaceutical agents, particularly those targeting respiratory and cardiovascular pathways. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of advanced theophylline derivatives and potential new chemical entities (NCEs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop compounds with modified pharmacokinetic or receptor-binding profiles.
• Process Development: Employed in scaling up and optimizing synthetic routes for active pharmaceutical ingredients (APIs) in pilot plants.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Biochemical Research: Investigated for its interaction with adenosine receptors and related enzymatic pathways in experimental models.

Basic Information

Product Name	7-γ-(β-Hydroxypropyl)Theophylline 2',4'-Dichlorobenzoate
CAS No.	117782-63-5
Molecular Formula	C20H22Cl2N4O5
Molecular Weight	469.32 g/mol
Synonyms	7-(2-Hydroxypropyl)-1,3-dimethylxanthine 2',4'-Dichlorobenzoate; 7-(β-Hydroxypropyl)theophylline 2,4-Dichlorobenzoate; 1,3-Dimethyl-7-(2-hydroxypropyl)xanthine 2',4'-Dichlorobenzoate; Theophylline-7-(2-hydroxypropyl) 2,4-dichlorobenzoate; 7-HPT 2',4'-DCB; 7-(2-Hydroxypropyl)theophylline dichlorobenzoate; 7-γ-(β-Hydroxypropyl)theophylline 2',4'-dichlorobenzoate
EINECS	Contact for details

Quality Control

Our 7-γ-(β-Hydroxypropyl)Theophylline 2',4'-Dichlorobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research and development use. Certificates of Analysis (COA) with complete batch data are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic; therefore, the container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.