Description

(2Rs,5R)-Menthone-2,6,6-D3 is a deuterium-labeled stereoisomer of menthone, a key monoterpenoid ketone. This labeled compound is essential for advanced analytical and research applications where isotopic tracing is required, offering a non-radioactive, stable isotopic marker. It is primarily needed by research institutions, pharmaceutical development labs, and flavor & fragrance manufacturers engaged in metabolic studies, reaction mechanism elucidation, and internal standard preparation for mass spectrometry.

Application

• Internal Standard for GC/MS and LC/MS Analysis: Used as a deuterated internal standard for the accurate quantification of menthone and related terpenoids in complex matrices.
• Metabolic Pathway Tracing: Employed in pharmacokinetic and metabolic studies to track the absorption, distribution, metabolism, and excretion (ADME) of terpene-based compounds.
• Mechanistic Reaction Studies: Serves as a tracer in organic chemistry research to investigate reaction pathways, isomerization processes, and catalytic mechanisms involving ketones.
• Flavor and Fragrance Research: Used in stability testing and authenticity verification of natural mint oils and synthetic flavor blends.
• Deuterated Building Block: Acts as a specialized starting material for the synthesis of more complex deuterium-labeled flavor, fragrance, or pharmaceutical intermediates.
• NMR Spectroscopy: Useful as a probe in nuclear magnetic resonance studies due to the distinct signal of deuterium atoms.

Basic Information

Product Name	(2Rs,5R)-Menthone-2,6,6-D3
CAS No.	117773-78-1
Molecular Formula	C10H15D3O
Molecular Weight	155.26 g/mol
Synonyms	(2R,5R)-p-Menthane-3-one-2,6,6-D3; (-)-Menthone-2,6,6-D3; (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanone-2,6,6-D3; L-Menthone-2,6,6-D3; (2R,5R)-2-Isopropyl-5-methylcyclohexanone-2,6,6-D3; Deuterated L-Menthone; p-Menth-8-en-3-one-2,6,6-D3 (stereospecific)
EINECS	Contact for details

Quality Control

Every batch of (2Rs,5R)-Menthone-2,6,6-D3 is produced and analyzed under strict quality protocols. We ensure high chemical purity, isotopic enrichment, and stereochemical integrity through advanced analytical techniques. Certificates of Analysis (COA) detailing purity (by GC or HPLC), isotopic enrichment (by MS or NMR), and specific rotation are provided with each shipment to guarantee consistency for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed when not in use to prevent evaporation and potential concentration changes.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Isotopic Enrichment (D3)	≥ 98 atom % D
Specific Rotation [α]20/D	-24° to -30° (c=1 in ethanol)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.