Description

Doramectin CAS NO 117704-25-3 is a semi-synthetic macrocyclic lactone belonging to the avermectin class of compounds, renowned for its potent antiparasitic activity. This high-purity active pharmaceutical ingredient (API) is critical for developing effective and reliable veterinary endectocide formulations. It is primarily required by manufacturers in the animal health and pharmaceutical industries for producing injectable solutions, pour-ons, and feed additives to control internal and external parasites in livestock.

Application

• Veterinary Injectable Solutions: Primary active ingredient for long-acting parasiticidal injections for cattle and swine.
• Livestock Pour-On Formulations: Key component in topical applications for systemic control of parasites in cattle.
• Animal Feed Additives: Used in medicated feeds for the prevention and treatment of parasitic infestations.
• Broad-Spectrum Endectocide Production: Manufacture of products effective against nematodes, mites, lice, and ticks.
• Veterinary Pharmaceutical Intermediates: Serves as a critical intermediate in synthesizing finished dosage forms.
• Research & Development: Used in biochemical research for studying parasite neurobiology and developing new antiparasitic agents.

Basic Information

Product Name	Doramectin
CAS No.	117704-25-3
Molecular Formula	C₅₀H₇₄O₁₄
Molecular Weight	899.12 g/mol
Synonyms	Dectomax; 25-Cyclohexyl-5-O-demethyl-25-de(1-methylpropyl)avermectin A1a; (1R,4S,5'S,6R,6'R,8R,10E,12S,13S,14E,16E,20R,21R,24S)-6'-[(S)-sec-Butyl]-21,24-dihydroxy-5',11,13,22-tetramethyl-2-oxo-3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6-spiro-2'-(5',6'-dihydro-2'H-pyran)-12-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-3-O-methyl-α-L-arabino-hexopyranoside
EINECS	Contact for details

Quality Control

Our Doramectin is manufactured under strict quality management systems to ensure it meets the high standards required for pharmaceutical use. Each batch undergoes comprehensive analytical testing, including HPLC for assay and related substances, residual solvent analysis, and microbiological examination. Certificates of Analysis (COA) documenting compliance with in-house specifications are available upon request, supporting your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Microbial Limits	Meets Ph. Eur. 2.6.12/2.6.13

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.