Description

Isoquinolinium, 1,2,3,4-Tetrahydro-2-(3-Hydroxypropyl)-6,7-Dimethoxy-2-Methyl-1-[(3,4,5-Trimethoxyphenyl)Methyl]-, Chloride, (1R)- (9Ci) is a complex, chiral isoquinolinium salt derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound matters as a sophisticated chemical building block and pharmacological intermediate, enabling the development of novel therapeutic agents. It is primarily needed by research institutions and pharmaceutical companies engaged in the discovery and synthesis of new chemical entities, particularly those targeting neurological and cardiovascular pathways.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of potential drug candidates, especially for central nervous system (CNS) and cardiovascular targets.
• Biochemical Research: Used as a tool compound or ligand in enzymatic and receptor binding studies due to its complex, multi-functional structure.
• Asymmetric Synthesis: Acts as a chiral template or catalyst component in stereoselective organic reactions.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties of lead molecules.
• Reference Standard: Utilized as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	Isoquinolinium, 1,2,3,4-Tetrahydro-2-(3-Hydroxypropyl)-6,7-Dimethoxy-2-Methyl-1-[(3,4,5-Trimethoxyphenyl)Methyl]-, Chloride, (1R)- (9Ci)
CAS No.	117676-61-6
Molecular Formula	C25H34ClNO6
Molecular Weight	480.00 g/mol (approx.)
Synonyms	(1R)-1,2,3,4-Tetrahydro-2-(3-hydroxypropyl)-6,7-dimethoxy-2-methyl-1-[(3,4,5-trimethoxyphenyl)methyl]isoquinolinium Chloride; (R)-1,2,3,4-Tetrahydro-2-(3-hydroxypropyl)-6,7-dimethoxy-2-methyl-1-(3,4,5-trimethoxybenzyl)isoquinolinium Chloride; 1,2,3,4-Tetrahydro-2-(3-hydroxypropyl)-6,7-dimethoxy-2-methyl-1-[(3,4,5-trimethoxyphenyl)methyl]isoquinolinium Chloride, (R)-; 1,2,3,4-Tetrahydro-2-(3-hydroxypropyl)-6,7-dimethoxy-2-methyl-1-(3,4,5-trimethoxybenzyl)isoquinolinium Chloride; (R)-Tetrahydroberberine Derivative Chloride Salt
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) are available upon request, detailing specifications such as chiral purity, chemical purity, and residual solvent content. We adhere to a cGMP-compliant quality management system suitable for pharmaceutical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere if specified. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.