Description

3-Hydrazinyl-8-Methyl-5H-[1,2,4]Triazino[5,6-B]Indole is a high-purity, advanced heterocyclic building block of significant interest in modern organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmacologically active molecules, particularly within the fields of oncology and central nervous system (CNS) research. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of complex fused-ring systems for drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates targeting specific biological pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Oncology Research: Employed in the development of potential kinase inhibitors and other targeted cancer therapies.
• CNS Drug Discovery: Utilized in creating compounds for investigating neurological disorders.
• Chemical Biology: Acts as a probe or tool compound for studying enzyme function and protein-ligand interactions.
• Process Chemistry: Used in route scouting and scale-up optimization for the production of active pharmaceutical ingredients (APIs).
• Academic Research: A valuable reagent for universities and institutes studying heterocyclic chemistry and novel reaction methodologies.

Basic Information

Product Name	3-Hydrazinyl-8-Methyl-5H-[1,2,4]Triazino[5,6-B]Indole
CAS No.	117480-53-2
Molecular Formula	C12H11N7
Molecular Weight	253.27 g/mol
Synonyms	8-Methyl-3-hydrazinyl-5H-[1,2,4]triazino[5,6-b]indole; 3-Hydrazino-8-methyl-5H-[1,2,4]triazino[5,6-b]indole; 8-Methyl-5H-[1,2,4]triazino[5,6-b]indol-3-ylhydrazine; 117480-53-2; [1,2,4]Triazino[5,6-b]indole, 3-hydrazinyl-8-methyl-5H-; 5H-[1,2,4]Triazino[5,6-b]indole, 3-hydrazinyl-8-methyl-
EINECS	Contact for details

Quality Control

Our 3-Hydrazinyl-8-Methyl-5H-[1,2,4]Triazino[5,6-B]Indole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC for assay and purity determination, to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.