Description

14B-(p-Chlorocinnamoylamino)-7,8-Dihydro-n-Cyclopropylmethylmorphinone Mesylate is a high-purity, specialized pharmaceutical intermediate and research chemical. This compound is critical for advanced pharmacological research and development, particularly in the study of opioid receptor activity and the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on neuropharmacology and analgesic development.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of novel opioid receptor ligands and analgesic compounds.
• Biochemical Research: Used as a reference standard and active agent in studies investigating pain pathways, receptor binding affinity, and signal transduction mechanisms.
• Medicinal Chemistry: Serves as a core structure for the design and development of new chemical entities (NCEs) with potential therapeutic applications.
• Preclinical Studies: Employed in in vitro and in vivo models to assess pharmacological profiles, efficacy, and safety parameters.
• Reference Material: Provides a high-purity standard for analytical method development, validation, and quality control in pharmaceutical analysis.

Basic Information

Product Name	14B-(p-Chlorocinnamoylamino)-7,8-Dihydro-n-Cyclopropylmethylmorphinone Mesylate
CAS No.	117332-69-1
Molecular Formula	C28H31ClN2O5S
Molecular Weight	543.08 g/mol
Synonyms	14β-(p-Chlorocinnamoylamino)-7,8-dihydro-N-cyclopropylmethylnormorphinone mesylate; 14β-(4-Chlorocinnamamido)-7,8-dihydro-N-cyclopropylmethylnormorphinone methanesulfonate; Buprenorphine related compound; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 14B-(p-Chlorocinnamoylamino)-7,8-Dihydro-n-Cyclopropylmethylmorphinone Mesylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation via spectroscopic methods (IR, NMR, MS), and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or cGMP guidelines. Specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.