Description

3-Chloro-4-Hydroxy-5-Azaindole is a high-purity, heterocyclic organic compound that serves as a critical advanced intermediate in modern pharmaceutical synthesis. Its unique fused-ring structure, featuring both chloro and hydroxy substituents, makes it a versatile building block for constructing complex molecules with targeted biological activity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on creating novel kinase inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of potent kinase inhibitors and other targeted cancer therapies.
• Agrochemical Research: Used as a core scaffold for developing new active ingredients in crop protection products.
• Chemical Biology: Serves as a probe or precursor in the study of enzyme mechanisms and protein-ligand interactions.
• Organic Synthesis: A versatile building block for constructing complex heterocyclic systems and fused-ring architectures in medicinal chemistry.
• Material Science Research: Potential precursor for organic electronic materials due to its electron-rich indole-like structure.

Basic Information

Product Name	3-Chloro-4-Hydroxy-5-Azaindole
CAS No.	117332-46-4
Molecular Formula	C7H5ClN2O
Molecular Weight	168.58 g/mol
Synonyms	3-Chloro-1H-pyrrolo[3,2-b]pyridin-4-ol; 4-Hydroxy-3-chloro-1H-pyrrolo[3,2-b]pyridine; 3-Chloro-4-hydroxy-1H-pyrrolo[3,2-b]pyridine; 5-Azaindole, 3-chloro-4-hydroxy-; 3-Chloro-4-hydroxy-7-azaindole
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Hydroxy-5-Azaindole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.