Description

7-Methoxy-1,2-Dihydrocyclopenta[B]Indol-3(4H)-One is a high-purity, synthetically derived organic compound belonging to the class of cyclopenta[b]indole derivatives, serving as a critical advanced intermediate in pharmaceutical research and development. This compound matters because it provides a structurally complex and versatile scaffold for synthesizing novel therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery. Pharmaceutical companies, biotechnology research firms, and advanced fine chemical manufacturers need this high-value intermediate to develop next-generation small molecule drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting specific enzymatic pathways.
• Oncology Research: Used in the development of novel kinase inhibitors and other targeted cancer therapies due to its privileged heterocyclic structure.
• CNS Drug Discovery: Serves as a core scaffold for creating compounds with potential activity against neurological disorders.
• Chemical Biology & Proteomics: Employed in the design of molecular probes and tool compounds for studying biological mechanisms.
• Process Chemistry & Scale-Up: Utilized in route scouting and optimization for the commercial-scale production of active pharmaceutical ingredients (APIs).
• Academic & Contract Research: A valuable reagent for universities and CROs conducting cutting-edge medicinal chemistry programs.

Basic Information

Product Name	7-Methoxy-1,2-Dihydrocyclopenta[B]Indol-3(4H)-One
CAS No.	117311-14-5
Molecular Formula	C12H11NO2
Molecular Weight	201.22 g/mol
Synonyms	7-Methoxy-1,2,3,4-tetrahydrocyclopenta[b]indol-3-one; 3H-Cyclopenta[b]indol-3-one, 1,2-dihydro-7-methoxy-; 7-Methoxy-1,2-dihydro-3H-cyclopenta[b]indol-3-one; 7-Methoxy-1,2,3,4-tetrahydrocyclopentaindol-3-one; 7-Methoxy-1,2-dihydrocyclopentaindol-3-one; 7-Methoxy-1,2-dihydro-3H-cyclopentaindol-3-one
EINECS	Contact for details

Quality Control

Our 7-Methoxy-1,2-Dihydrocyclopenta[B]Indol-3(4H)-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with cGMP and ISO standards for pharmaceutical intermediates, and specifications can be aligned with client-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.