Description

1,1,1,2-Tetrachloroethane-D2 is a deuterated isotopologue of 1,1,1,2-tetrachloroethane, where two hydrogen atoms are replaced by deuterium atoms. This deuteration makes it an invaluable internal standard and analytical tracer in quantitative mass spectrometry and NMR spectroscopy, providing superior accuracy by eliminating signal interference from the non-deuterated compound. It is primarily used by researchers and quality control laboratories in the pharmaceutical, environmental, and chemical synthesis sectors for method development, metabolic studies, and precise impurity profiling.

Application

• Internal Standard for GC/MS and LC/MS: Used as a quantitative reference standard in the analysis of chlorinated solvents and environmental pollutants.
• NMR Spectroscopy Solvent & Tracer: Serves as a deuterated solvent or a mechanistic tracer in reaction monitoring and structural elucidation studies.
• Pharmaceutical Impurity Profiling: Critical for identifying and quantifying genotoxic impurities (GTIs) and process-related degradants in active pharmaceutical ingredients (APIs).
• Metabolic Pathway Research: Employed in isotopic labeling studies to track the metabolic fate of chlorinated compounds in biological systems.
• Environmental Analysis: Acts as a standard in the detection and quantification of tetrachloroethane and its metabolites in soil and water samples.
• Chemical Synthesis Intermediate: Used in specialized synthetic routes where deuterium incorporation is required.

Basic Information

Product Name	1,1,1,2-Tetrachloroethane-D2
CAS No.	117164-18-8
Molecular Formula	C2D2Cl4
Molecular Weight	171.86 g/mol
Synonyms	Deutero-1,1,1,2-tetrachloroethane; Tetrachloroethane-d2; 1,1,1,2-Tetrachloro[1,2-2H2]ethane; 1,1,1,2-Tetrachloroethane-1,2-d2; Perchloroethane-d2 (ambiguous); Ethane-d2, 1,1,1,2-tetrachloro-; NSC 406865-d2
EINECS	Contact for details

Quality Control

Every batch of 1,1,1,2-Tetrachloroethane-D2 is produced and analyzed under strict quality management protocols. We guarantee high chemical and isotopic purity, with comprehensive testing including assay, deuterium enrichment (D-enrichment), and impurity profiling via GC, HPLC, and NMR. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to ensure traceability and compliance with your research or quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place away from strong acids, bases, and oxidizing agents. Recommended storage temperature is 2-8°C to maintain stability and minimize volatility. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (GC)	≥ 98.0% (by area)
Deuterium Enrichment	≥ 98 atom % D
Water Content (KF)	≤ 0.1%
Residue on Evaporation	≤ 0.01%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.