Description

2-Chloroethanol-1,1,2,2-D4 is a deuterium-labeled isotopologue of 2-chloroethanol, a versatile chemical building block. This high-purity labeled compound is essential for advanced analytical and research applications where isotopic tracing is required. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for mechanistic studies, metabolic pathway analysis, and as an internal standard in quantitative mass spectrometry.

Application

• Internal Standard for Analytical Chemistry: Used in GC-MS, LC-MS, and NMR for the accurate quantification of 2-chloroethanol in complex matrices.
• Metabolic and Pharmacokinetic Studies: A critical tracer for investigating the absorption, distribution, metabolism, and excretion (ADME) of chloroethanol derivatives in biological systems.
• Mechanistic Organic Chemistry Research: Employed in reaction mechanism elucidation and kinetic isotope effect (KIE) studies due to its deuterium labels.
• Synthesis of Labeled Compounds: Serves as a key deuterated precursor for the synthesis of more complex isotopically labeled fine chemicals and active pharmaceutical ingredients (APIs).
• Environmental Fate Studies: Used to trace the environmental degradation and transformation pathways of chloroethanol and related compounds.

Basic Information

Product Name	2-Chloroethanol-1,1,2,2-D4
CAS No.	117067-62-6
Molecular Formula	C2D4H2ClO
Molecular Weight	84.53 g/mol
Synonyms	Ethylene Chlorohydrin-d4; 2-Chloroethyl-d4 Alcohol; 2-Chloro-1,1,2,2-tetradeuteroethanol; Deuterochloroethanol; Chloroethanol-d4; 1,1,2,2-Tetradeutero-2-chloroethanol; β-Chloroethanol-d4; NSC 8815-d4
EINECS	Contact for details

Quality Control

Every batch of 2-Chloroethanol-1,1,2,2-D4 is produced and analyzed under strict quality management protocols. We guarantee high chemical and isotopic purity, with comprehensive testing performed via NMR, GC-MS, and HPLC. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, isotopic enrichment, and absence of critical impurities. Our quality system supports compliance with cGMP and ISO standards for research and development materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong acids, bases, and oxidizing agents. Due to its highly volatile nature, ensure containers are kept upright and sealed when not in use. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 98.0%
Isotopic Enrichment (D)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.