Description

Boc-L-Phenylglycinol CAS NO 117049-14-6 is a protected amino alcohol derivative, serving as a crucial chiral building block in organic synthesis. Its primary value lies in providing a stereochemically defined scaffold for constructing complex molecules, particularly in the pharmaceutical sector. This high-purity intermediate is essential for researchers and manufacturers in pharmaceutical development, agrochemical synthesis, and advanced material science who require reliable, enantiomerically pure starting materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), especially protease inhibitors and other therapeutics.
• Peptide Mimetics & Conjugate Chemistry: Used to introduce the phenylglycinol moiety into peptide backbones to enhance stability and biological activity.
• Asymmetric Catalyst Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in asymmetric hydrogenation and other catalytic reactions.
• Agrochemical Synthesis: Building block for creating enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Material Science: Precursor for chiral polymers and advanced organic frameworks with specific optical properties.
• Academic & Process R&D: Valuable reagent for methodological development in organic chemistry and scale-up process optimization.

Basic Information

Product Name	Boc-L-Phenylglycinol
CAS No.	117049-14-6
Molecular Formula	C₁₃H₁₉NO₃
Molecular Weight	237.29 g/mol
Synonyms	(R)-2-((tert-Butoxycarbonyl)amino)-2-phenylethanol; (R)-N-Boc-2-Amino-2-phenylethanol; (R)-2-(Boc-amino)-2-phenylethanol; Boc-D-Phenylglycinol (enantiomer); tert-Butyl (R)-(2-hydroxy-1-phenylethyl)carbamate; N-(tert-Butoxycarbonyl)-L-phenylglycinol; (R)-N-Boc-β-amino-β-phenylethanol; L-Phenylglycinol, N-Boc-protected
EINECS	Contact for details

Quality Control

Our Boc-L-Phenylglycinol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Melting Point	82 - 86 °C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.