Description

n-((2,3-Dihydro-1,4-benzodioxin-2-yl)methyl)-5-methoxy-1H-indole-3-ethanamine is a high-purity, synthetic organic compound featuring a unique molecular architecture that combines indole and benzodioxane pharmacophores. This structure makes it a critical intermediate for advanced research and development in medicinal chemistry. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of novel bioactive molecules for preclinical studies.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential therapeutic agents targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to develop new drug candidates with modified receptor affinity.
• Biochemical Tool Compound: Employed in vitro and in vivo to study biological pathways and mechanisms associated with serotonin and related neurotransmitter systems.
• Reference Standard: Provides a high-purity standard for analytical method development, validation, and quality control in API manufacturing.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and early-stage drug development projects.

Basic Information

Product Name	n-((2,3-Dihydro-1,4-benzodioxin-2-yl)methyl)-5-methoxy-1H-indole-3-ethanamine
CAS No.	116729-30-7
Molecular Formula	C20H22N2O3
Molecular Weight	338.40 g/mol
Synonyms	5-Methoxy-α-methyltryptamine benzodioxane derivative; 2-(5-Methoxy-1H-indol-3-yl)-N-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]ethanamine; 116729-30-7; Ariadne; α-Methyl-5-methoxytryptamine benzodioxanyl analog; 5-MeO-AMT benzodioxane derivative
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced under strict quality management systems. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles, ensuring traceability and consistency for your critical R&D work. Our quality protocols are designed to meet the stringent requirements of pharmaceutical development and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 1.0%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.