Description

2-(((tert-Butyldimethylsilyl)Oxy)Methyl)Prop-2-En-1-Ol is a high-value organosilicon-protected alcohol derivative, specifically a silyl ether of an allylic alcohol. This compound is a crucial synthetic intermediate and protecting group reagent in advanced organic synthesis, prized for its ability to mask hydroxyl functionality under a wide range of reaction conditions. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the construction of complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing protected hydroxyl groups in complex molecules.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and pesticides.
• Polymer Chemistry: Serves as a functional monomer or chain-transfer agent in the development of specialty polymers with tailored properties.
• Material Science: Employed in the surface modification of materials and the synthesis of silicon-containing organic frameworks.
• Organic Synthesis Reagent: Acts as a versatile reagent for introducing the TBDMS-protected hydroxymethyl allyl moiety in multi-step synthetic routes.
• Asymmetric Catalysis: Used as a substrate or ligand precursor in catalytic asymmetric synthesis for creating chiral centers.

Basic Information

Product Name	2-(((tert-Butyldimethylsilyl)Oxy)Methyl)Prop-2-En-1-Ol
CAS No.	116700-73-3
Molecular Formula	C10H22O2Si
Molecular Weight	202.37 g/mol
Synonyms	2-[(tert-Butyldimethylsilyloxy)methyl]prop-2-en-1-ol; 2-((tert-Butyldimethylsilyloxy)methyl)allyl Alcohol; 2-(TBDMS-oxymethyl)allyl Alcohol; (2-Hydroxymethylallyloxy)-tert-butyldimethylsilane; 2-[(TBDMSO)methyl]allyl Alcohol; 2-(Hydroxymethyl)allyl tert-Butyldimethylsilyl Ether; TBDMS Ether of 2-(Hydroxymethyl)allyl Alcohol
EINECS	Contact for details

Quality Control

Our 2-(((tert-Butyldimethylsilyl)Oxy)Methyl)Prop-2-En-1-Ol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.