Description

(S)-3-Amino-1,2,3,4-Tetrahydrocarbazole CAS NO 116650-34-1 is a chiral, non-natural amino acid derivative featuring a fused tetrahydrocarbazole scaffold. This compound serves as a versatile and high-value chiral building block in modern organic synthesis, particularly for constructing complex molecules with defined stereochemistry. It is primarily utilized by pharmaceutical research and development teams engaged in the discovery of new active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potential drug candidates, particularly in neurological and psychiatric therapeutic areas.
• Asymmetric Catalysis Research: Used as a ligand precursor or a chiral auxiliary in the development of novel catalytic systems.
• Medicinal Chemistry: Core scaffold for constructing focused libraries to explore structure-activity relationships (SAR) in drug discovery programs.
• Chemical Biology: Incorporation into molecular probes to study enzyme mechanisms or protein-ligand interactions.
• Academic Research: Serves as a starting material for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	(S)-3-Amino-1,2,3,4-Tetrahydrocarbazole
CAS No.	116650-34-1
Molecular Formula	C12H14N2
Molecular Weight	186.26 g/mol
Synonyms	(S)-3-Amino-1,2,3,4-tetrahydro-9H-carbazole; (3S)-1,2,3,4-Tetrahydro-9H-carbazol-3-amine; (S)-Tetrahydrocarbazol-3-ylamine; (S)-3-Amino-1,2,3,4-tetrahydrocarbazole; (S)-THCA; (S)-Aminotetrahydrocarbazole; (3S)-Aminotetrahydrocarbazole; (S)-3-ATHC
EINECS	Contact for details

Quality Control

Our production of (S)-3-Amino-1,2,3,4-Tetrahydrocarbazole adheres to stringent quality protocols suitable for research and development applications. Each batch is characterized and tested to ensure high chiral purity and chemical identity. Our standard quality commitment includes comprehensive analysis via HPLC, NMR, and optical rotation. Certificates of Analysis (COA) detailing purity, enantiomeric excess (ee), and full analytical data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to prevent moisture absorption, which may affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (ee)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.