Description

(R)-3-Amino-1,2,3,4-Tetrahydrocarbazole CAS NO 116650-33-0 is a chiral, non-natural amino acid derivative featuring a fused tetrahydrocarbazole scaffold. This compound serves as a versatile and high-value chiral building block in asymmetric synthesis, prized for its rigid, three-dimensional structure. It is primarily utilized by pharmaceutical research and development organizations for the discovery and synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology therapeutic areas.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates and bioactive molecules.
• Asymmetric Catalysis Research: Used as a precursor or ligand in the development of new chiral catalysts and auxiliaries.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to explore novel chemical space and improve drug-like properties.
• Process Chemistry Development: Serves as a starting material for scaling up synthetic routes to target compounds under Good Manufacturing Practice (GMP) conditions.
• Academic & Institutional Research: Utilized in chemical biology and organic synthesis research projects focusing on alkaloid analogs and heterocyclic chemistry.

Basic Information

Product Name	(R)-3-Amino-1,2,3,4-Tetrahydrocarbazole
CAS No.	116650-33-0
Molecular Formula	C12H14N2
Molecular Weight	186.25 g/mol
Synonyms	(R)-3-Amino-1,2,3,4-tetrahydro-9H-carbazole; (R)-1,2,3,4-Tetrahydro-9H-carbazol-3-amine; (3R)-1,2,3,4-Tetrahydrocarbazol-3-amine; (R)-Tetrahydrocarbazol-3-amine; (R)-THCA; (R)-3-ATCA; (R)-3-Amino-1,2,3,4-tetrahydrocarbazole
EINECS	Contact for details

Quality Control

Our (R)-3-Amino-1,2,3,4-Tetrahydrocarbazole is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with high-purity research and development standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment and opened under dry, inert conditions to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.