Description

3-Thiophenecarboxylicacid,5-Amino- CAS NO 116539-01-6 is a high-purity, functionalized heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in the strategic combination of a carboxylic acid group and an amino group on a thiophene ring, enabling its use as a versatile precursor for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, particularly for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in therapeutic areas targeting the central nervous system and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the thiophene moiety can contribute to specific biological activity.
• Functional Material Precursor: Serves as a monomer or building block for conductive polymers, organic semiconductors, and non-linear optical (NLO) materials.
• Ligand and Catalyst Development: The amino and carboxyl groups make it a useful starting material for creating chelating ligands and organocatalysts in asymmetric synthesis.
• Dye and Pigment Manufacturing: Employed in the synthesis of specialized dyes and pigments for high-performance applications.
• Academic and R&D: A valuable reagent for methodological studies in organic chemistry and for exploring new chemical spaces in drug discovery programs.

Basic Information

Product Name	3-Thiophenecarboxylicacid,5-Amino- CAS NO 116539-01-6
CAS No.	116539-01-6
Molecular Formula	C5H5NO2S
Molecular Weight	143.16 g/mol
Synonyms	5-Aminothiophene-3-carboxylic acid; 3-Thiophenecarboxylic acid, 5-amino-; 5-Amino-3-thiophenecarboxylic acid; 5-Amino-3-carboxythiophene; 3-Carboxy-5-aminothiophene; 5-Amino-thiophene-3-carboxylic acid; 5-Amino-3-thiophene carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 3-Thiophenecarboxylicacid,5-Amino- is produced and tested under a strict quality management system to ensure consistency and reliability for your critical applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, and we can support development projects requiring material meeting specific pharmacopeial or internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Light yellow to brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.