Description

3-(3-Chlorophenyl)-4-Cyano-5-(Methylthio)Thiophene-2-Carboxylic Acid is a high-value, multi-functional heterocyclic building block designed for advanced synthetic chemistry. This compound matters because it provides a versatile scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific chlorophenyl, cyano, and thioether functionalities into their target structures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Serves as a critical building block for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Research: Used in the development of organic semiconductors, conductive polymers, and non-linear optical (NLO) materials due to its electron-rich thiophene core.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-(3-Chlorophenyl)-4-Cyano-5-(Methylthio)Thiophene-2-Carboxylic Acid
CAS No.	116493-00-6
Molecular Formula	C13H8ClNO2S2
Molecular Weight	309.79 g/mol
Synonyms	3-(3-Chlorophenyl)-4-cyano-5-(methylthio)thiophene-2-carboxylic acid; 2-Thiophenecarboxylic acid, 3-(3-chlorophenyl)-4-cyano-5-(methylthio)-; 5-(Methylthio)-3-(3-chlorophenyl)-4-cyanothiophene-2-carboxylic acid; 3-(3-Chlorophenyl)-5-(methylthio)-4-cyanothiophene-2-carboxylic acid; 4-Cyano-3-(3-chlorophenyl)-5-(methylthio)thiophene-2-carboxylic acid; 116493-00-6; Thiophene-2-carboxylic acid derivative
EINECS	Contact for details

Quality Control

Our production of 3-(3-Chlorophenyl)-4-Cyano-5-(Methylthio)Thiophene-2-Carboxylic Acid adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC, NMR, and MS for comprehensive characterization. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. Our quality system is designed to support cGMP (current Good Manufacturing Practice) requirements for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment. Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.