Description

4-Cyano-5-(Methylthio)-3-[3-(Trifluoromethyl)Phenyl]Thiophene-2-Carboxylic Acid is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. Its core value lies in its unique molecular architecture, which incorporates a thiophene core, a carboxylic acid, a nitrile group, and a trifluoromethylphenyl moiety, making it an essential intermediate for creating complex molecules with tailored properties. This compound is critically needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly in the development of small molecule drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in therapeutic areas targeting enzymes and receptors where the trifluoromethyl group enhances metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for biological activity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of advanced polymers and organic electronic materials.
• Chemical Synthesis Scaffold: The reactive carboxylic acid and nitrile groups allow for further derivatization (amidation, esterification, hydrolysis) to create diverse chemical libraries for screening.
• Ligand Synthesis: Useful in the preparation of specialized ligands for catalysis or metal-organic frameworks (MOFs).

Basic Information

Product Name	4-Cyano-5-(Methylthio)-3-[3-(Trifluoromethyl)Phenyl]Thiophene-2-Carboxylic Acid
CAS No.	116492-99-0
Molecular Formula	C14H8F3NO2S2
Molecular Weight	343.34 g/mol
Synonyms	3-[3-(Trifluoromethyl)phenyl]-4-cyano-5-(methylthio)thiophene-2-carboxylic acid; 4-Cyano-5-methylsulfanyl-3-[3-(trifluoromethyl)phenyl]thiophene-2-carboxylic acid; 2-Thiophenecarboxylic acid, 4-cyano-5-(methylthio)-3-[3-(trifluoromethyl)phenyl]-; 116492-99-0; 4-Cyano-5-(methylthio)-3-(3-trifluoromethylphenyl)thiophene-2-carboxylic Acid
EINECS	Contact for details

Quality Control

Our 4-Cyano-5-(Methylthio)-3-[3-(Trifluoromethyl)Phenyl]Thiophene-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.