Description

3-(1-Methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indol-5-amine is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. It is essential for research and development laboratories, process chemists, and manufacturers in the pharmaceutical and fine chemical industries seeking reliable, high-quality intermediates for complex synthetic routes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly for neurological and psychiatric disorders.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemists exploring new structure-activity relationships (SAR) in drug discovery programs.
• API Synthesis: Used in the multi-step manufacturing process of final Active Pharmaceutical Ingredients (APIs) requiring high regiochemical and stereochemical control.
• Biochemical Research: Employed in the study of receptor-ligand interactions and as a tool compound in pharmacological assays.
• Fine Chemical Production: Integral to the custom synthesis of specialty chemicals for advanced material science and agrochemical research.

Basic Information

Product Name	3-(1-Methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indol-5-amine
CAS No.	116480-62-7
Molecular Formula	C14H17N3
Molecular Weight	227.31 g/mol
Synonyms	5-Amino-3-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole; 1H-Indol-5-amine, 3-(1-methyl-1,2,3,6-tetrahydro-4-pyridinyl)-; 3-(1-Methyl-4-piperidinylidene)-1H-indol-5-amine; 5-Amino-3-(1-methyl-4-piperidinylidene)indole; 116480-62-7; 3-(1-Methyl-1,2,3,6-tetrahydro-4-pyridinyl)-1H-indol-5-amine
EINECS	Contact for details

Quality Control

Our 3-(1-Methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indol-5-amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.