Description

Methyl 1-(Phenylsulfonyl)-1H-Indole-3-Carboxylate is a high-value, synthetically versatile sulfonamide-protected indole derivative. This compound serves as a critical advanced pharmaceutical intermediate (API) and a key building block in modern organic synthesis. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active compounds. Its structure makes it an essential precursor for creating complex molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new generation herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Reagent: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and other transformations to construct complex heterocyclic systems.
• Material Science Precursor: Acts as a monomer or intermediate in the synthesis of specialty polymers and organic electronic materials.
• Academic & R&D: A valuable tool for medicinal chemistry research and methodology development in university and corporate laboratories.

Basic Information

Product Name	Methyl 1-(Phenylsulfonyl)-1H-Indole-3-Carboxylate
CAS No.	116325-17-8
Molecular Formula	C16H13NO4S
Molecular Weight	315.34 g/mol
Synonyms	1-(Phenylsulfonyl)-1H-indole-3-carboxylic acid methyl ester; Methyl 1-(benzenesulfonyl)-1H-indole-3-carboxylate; 1H-Indole-3-carboxylic acid, 1-(phenylsulfonyl)-, methyl ester; 1-Benzenesulfonylindole-3-carboxylic acid methyl ester; 3-(Methoxycarbonyl)-1-(phenylsulfonyl)indole; 1-Phenylsulfonylindole-3-carboxylic Acid Methyl Ester; 116325-17-8; Methyl 1-(Phenylsulfonyl)indole-3-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 1-(Phenylsulfonyl)-1H-Indole-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.