Description

4-(4-Chlorophenyl)-2,3-Dihydro-1,5-Benzothiazepine-2-Carboxylic Acid is a high-purity organic compound with the CAS number 116274-72-7, serving as a key advanced pharmaceutical intermediate. This compound is valued for its role in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of therapeutic agents targeting the central nervous and cardiovascular systems. It is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and contract research organizations (CROs) engaged in innovative drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel benzothiazepine-based drug candidates.
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a precursor in the multi-step manufacturing of complex APIs.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
• Process Development: Utilized in scaling up and optimizing synthetic routes for commercial production.
• Academic & Industrial Research: A valuable reagent for investigating heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Product Name	4-(4-Chlorophenyl)-2,3-Dihydro-1,5-Benzothiazepine-2-Carboxylic Acid
CAS No.	116274-72-7
Molecular Formula	C₁₆H₁₂ClNO₂S
Molecular Weight	317.79 g/mol
Synonyms	4-(4-Chlorophenyl)-2,3-dihydro-1,5-benzothiazepine-2-carboxylic acid; 2,3-Dihydro-4-(4-chlorophenyl)-1,5-benzothiazepine-2-carboxylic Acid; 1,5-Benzothiazepine-2-carboxylic acid, 4-(4-chlorophenyl)-2,3-dihydro-; 116274-72-7; 4-(p-Chlorophenyl)-2,3-dihydro-1,5-benzothiazepine-2-carboxylic acid; Benzothiazepine-2-carboxylic acid derivative; 4-(4-Chlorophenyl)-2,3-dihydro-1,5-benzothiazepine-2-carboxylic acid (CAS 116274-72-7)
EINECS	Contact for details

Quality Control

Our 4-(4-Chlorophenyl)-2,3-Dihydro-1,5-Benzothiazepine-2-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided, detailing results from HPLC, NMR, and other relevant tests to confirm compliance with customer specifications and internal standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.