Description

1H-2-Benzopyran-1-One,3,4-Dihydro-3-Hydroxy-(9Ci) is a high-purity synthetic intermediate belonging to the class of dihydrocoumarin derivatives. This compound is valued for its chiral hydroxyl group and lactone structure, making it a versatile building block in advanced organic synthesis. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

This specialized intermediate serves critical roles in sophisticated chemical synthesis processes. Key application areas include:

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Fine Chemical Synthesis: Used as a building block for creating flavors, fragrances, and other high-value specialty chemicals.
• Organic Chemistry Research: Employed in academic and industrial R&D for method development and exploring novel synthetic pathways.
• Agrochemical Development: Acts as an intermediate in the research and production of advanced crop protection agents.
• Material Science: Investigated for potential use in polymer modification and advanced material precursors.

Basic Information

Product Name	1H-2-Benzopyran-1-One,3,4-Dihydro-3-Hydroxy-(9Ci)
CAS No.	116206-41-8
Molecular Formula	C9H8O3
Molecular Weight	164.16 g/mol
Synonyms	3-Hydroxy-3,4-dihydro-1H-2-benzopyran-1-one; 3-Hydroxy-3,4-dihydroisocoumarin; 3,4-Dihydro-3-hydroxy-1H-2-benzopyran-1-one; 3-Hydroxydihydroisocoumarin; Dihydro-3-hydroxyisocoumarin; (3R)-3-Hydroxy-3,4-dihydro-1H-isochromen-1-one (enantiomer); (3S)-3-Hydroxy-3,4-dihydro-1H-isochromen-1-one (enantiomer)
EINECS	Contact for details

Quality Control

Our 1H-2-Benzopyran-1-One,3,4-Dihydro-3-Hydroxy-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.