Description

B-Alanine-2,2,3,3-D4 CAS NO 116173-67-2 is a stable isotope-labeled analog of the non-essential amino acid β-alanine, where four hydrogen atoms are replaced by deuterium. This high-purity labeled compound is essential for advanced analytical research, providing a critical internal standard for precise quantification and metabolic pathway tracing. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and analytical chemistry sectors for applications in mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy.

Application

• Internal Standard for Mass Spectrometry (MS): Used for the accurate quantification of β-alanine and related metabolites in complex biological matrices via LC-MS/MS and GC-MS.
• Metabolic Pathway Tracing: Enables detailed studies of carnosine synthesis, energy metabolism, and other biochemical pathways involving β-alanine.
• NMR Spectroscopy Studies: Serves as a valuable probe for structural and dynamic studies in solution-state NMR due to the distinct properties of deuterium.
• Pharmaceutical R&D: Employed in the development and validation of bioanalytical methods for drug metabolism and pharmacokinetics (DMPK) studies.
• Nutritional & Sports Science Research: Facilitates precise measurement of β-alanine uptake and its role in muscle carnosine loading.
• Stable Isotope Labeled Reference Material: Provides a certified reference material for quality control and method calibration in analytical laboratories.

Basic Information

Product Name	B-Alanine-2,2,3,3-D4
CAS No.	116173-67-2
Molecular Formula	C3D4H3NO2
Molecular Weight	93.11 g/mol
Synonyms	3-Aminopropanoic acid-2,2,3,3-d4; β-Alanine-d4; DL-β-Alanine-2,2,3,3-d4; 3-Aminopropionic acid-d4; Deuterated β-alanine; (2,2,3,3-2H4)-3-Aminopropanoic acid; Abufene-d4; Beta Alanine D4
EINECS	Contact for details

Quality Control

Our B-Alanine-2,2,3,3-D4 is manufactured under strict quality systems to ensure exceptional isotopic and chemical purity, meeting the rigorous demands of analytical research. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic purity (atom % D), chemical purity (by HPLC), and identification. We adhere to relevant industry standards for high-purity reference materials, and custom specifications or GMP-grade material can be discussed based on project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions after opening to maintain stability and prevent isotopic exchange.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Isotopic Purity	≥ 98 atom % D
Chemical Purity	≥ 95%
Residual Solvent (GC)	Meets ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.