Description

5-Acetyl-4-Amino-2-(Methylthio)Thiophene-3-Carbonitrile is a high-value, multi-functional heterocyclic building block with a unique thiophene core. This compound is critical for the synthesis of complex organic molecules, offering a versatile scaffold for introducing key functional groups. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material science sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging its thiophene moiety for enhanced biological activity.
• Organic Electronic Materials: Serves as a building block for π-conjugated systems in the research and development of organic semiconductors, OLEDs, and sensors.
• Dye and Pigment Chemistry: Acts as an intermediate for synthesizing specialized heterocyclic dyes and pigments with specific light-absorption properties.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring novel organic reactions and constructing complex molecular libraries.
• Ligand and Catalyst Development: Utilized to create novel chelating ligands for metal catalysts used in asymmetric synthesis and cross-coupling reactions.

Basic Information

Product Name	5-Acetyl-4-Amino-2-(Methylthio)Thiophene-3-Carbonitrile
CAS No.	116171-01-8
Molecular Formula	C9H8N2OS2
Molecular Weight	224.30 g/mol
Synonyms	2-(Methylthio)-5-acetyl-4-aminothiophene-3-carbonitrile; 4-Amino-5-acetyl-2-(methylthio)thiophene-3-carbonitrile; 5-Acetyl-4-amino-2-methylsulfanylthiophene-3-carbonitrile; 3-Cyano-4-amino-5-acetyl-2-(methylthio)thiophene; Thiophene-3-carbonitrile, 5-acetyl-4-amino-2-(methylthio)-; 116171-01-8
EINECS	Contact for details

Quality Control

Our 5-Acetyl-4-Amino-2-(Methylthio)Thiophene-3-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.