Description

1,2,3,4-Tetrahydroisoquinoline-4-Carboxylic Acid is a versatile heterocyclic building block of significant interest in advanced organic synthesis. Its unique fused ring structure makes it a critical intermediate for the development of novel pharmaceuticals and bioactive compounds. This high-purity chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to create complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates targeting central nervous system (CNS) disorders, cardiovascular diseases, and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its heterocyclic scaffold.
• Fine Chemical Building Block: Employed in the construction of complex organic molecules for material science and specialty chemical applications.
• Biochemical Research: Serves as a scaffold or precursor in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Alkaloid Analog Synthesis: Used to create synthetic analogs of natural tetrahydroisoquinoline alkaloids for biological evaluation.

Basic Information

Product Name	1,2,3,4-Tetrahydroisoquinoline-4-Carboxylic Acid
CAS No.	116140-19-3
Molecular Formula	C10H11NO2
Molecular Weight	177.20 g/mol
Synonyms	4-Carboxy-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-4-isoquinolinecarboxylic Acid; THIQ-4-COOH; 1,2,3,4-Tetrahydroisoquinoline-4-carboxylate; 4-(Carboxymethyl)-3,4-dihydroisoquinoline; 116140-19-3; (1,2,3,4-Tetrahydroisoquinolin-4-yl)formic acid
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetrahydroisoquinoline-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.