Description

N,n-Dimethylacetamide-D9 CAS NO 116057-81-9 is a deuterated analog of the widely used polar aprotic solvent N,N-Dimethylacetamide (DMAc), where all nine hydrogen atoms are replaced with deuterium. This high isotopic purity makes it an indispensable tool in advanced research and analytical chemistry, particularly for Nuclear Magnetic Resonance (NMR) spectroscopy. It is primarily sought after by pharmaceutical R&D laboratories, academic research institutions, and chemical manufacturers engaged in reaction mechanism studies, solvent effect investigations, and the synthesis of labeled compounds.

Application

• NMR Spectroscopy Solvent: Used as a deuterated solvent for proton NMR, providing a non-interfering signal background for analyzing organic compounds and reaction mixtures.
• Reaction Mechanism Studies: Employed in kinetic isotope effect (KIE) studies to elucidate detailed pathways of chemical and enzymatic reactions.
• Synthesis of Deuterated Compounds: Serves as a deuterium source or a labeled precursor in the synthesis of more complex deuterated molecules for research.
• Polymer Science Research: Utilized in studies of polymer solubility and interactions where a deuterated environment is required for analytical techniques like NMR.
• Pharmaceutical Development: Applied in metabolic studies and the development of deuterated drug candidates, where isotopic labeling is crucial for tracking and stability.
• Analytical Reference Standard: Acts as a high-purity internal standard or reference material in mass spectrometry and other quantitative analytical methods.

Basic Information

Product Name	N,n-Dimethylacetamide-D9
CAS No.	116057-81-9
Molecular Formula	C4D9NO
Molecular Weight	91.17 g/mol (for C4D9NO)
Synonyms	Deuterated DMAc; DMAc-d9; N,N-Dimethylacetamide-d9; Acetamide-D9, N,N-dimethyl-; Perdeuterated N,N-Dimethylacetamide; (Trideuteriomethyl)(oxodideuteriomethyl)dimethylazanium; Deuterated Solvent for NMR; Hexadeutero-acetic acid dimethyl-d3-amide
EINECS	Contact for details

Quality Control

Our N,n-Dimethylacetamide-D9 is produced and handled under stringent quality protocols to ensure exceptional isotopic and chemical purity, critical for sensitive spectroscopic applications. Each batch is analyzed to confirm deuterium enrichment (typically >99 atom % D) and the absence of protonated impurities. A comprehensive Certificate of Analysis (COA) detailing NMR purity, chemical assay, and water content is provided with every shipment to guarantee traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent absorption of atmospheric moisture and CO2, which can affect purity and performance.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms
Deuterium Content (NMR)	≥ 99 atom % D
Purity (GC)	≥ 99.5%
Water Content (KF)	≤ 0.05%
Protonated Impurity (¹H NMR)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.