Description

5-(4-Fluorophenyl)Thiophene-2-Carboxylic Acid is a high-value fluorinated heterocyclic building block essential for advanced organic synthesis. This compound matters as a key intermediate in the development of active pharmaceutical ingredients (APIs) and functional materials, offering a versatile scaffold for molecular diversification. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for creating novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in therapeutic areas requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the fluorophenyl-thiophene structure can contribute to specific biological activity.
• Material Science Precursor: Serves as a monomer or functional unit in the synthesis of specialty polymers, organic semiconductors, and liquid crystals.
• Chemical Synthesis Reagent: Employed in cross-coupling reactions, such as Suzuki or Stille couplings, to construct complex biaryl systems for various research applications.
• Ligand Synthesis: Utilized for creating novel ligands in catalysis and coordination chemistry due to the carboxylic acid and aromatic functionalities.

Basic Information

Product Name	5-(4-Fluorophenyl)Thiophene-2-Carboxylic Acid
CAS No.	115933-30-7
Molecular Formula	C11H7FO2S
Molecular Weight	222.24 g/mol
Synonyms	2-Thiophenecarboxylic acid, 5-(4-fluorophenyl)-; 5-(p-Fluorophenyl)-2-thiophenecarboxylic acid; 5-(4-Fluorophenyl)-2-thiophenecarboxylic acid; 5-(4-Fluorophenyl)thiophene-2-carboxylic acid; 115933-30-7; 4-Fluorophenyl-2-thiophenecarboxylic acid; 5-(4-Fluorophenyl)thiophene-2-carboxylate
EINECS	Contact for details

Quality Control

Our production of 5-(4-Fluorophenyl)Thiophene-2-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials are subjected to rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.