Description

Salicylic Acid-Ring-Ul-14C is a carbon-14 labeled isotopologue of salicylic acid, where the radioactive isotope is uniformly incorporated into the aromatic ring. This compound is essential for advanced metabolic and pharmacokinetic studies, providing a critical tool for tracing biochemical pathways with high specificity. It is primarily required by research institutions, pharmaceutical R&D departments, and contract research organizations (CROs) engaged in drug development, agricultural chemical research, and detailed metabolic profiling.

Application

• Drug Metabolism and Pharmacokinetics (DMPK) Studies: Used as a radiolabeled tracer to investigate the absorption, distribution, metabolism, and excretion (ADME) of salicylate-based pharmaceuticals and novel drug candidates.
• Biochemical Pathway Analysis: Enables precise tracking of the salicylic acid pathway in plant defense mechanisms and signaling studies.
• Environmental Fate Studies: Applied in research to monitor the degradation, transformation, and persistence of salicylic acid and related compounds in ecological systems.
• Analytical Method Development: Serves as an internal standard or reference material in the development and validation of sensitive LC-MS/MS, HPLC, and radio-HPLC methods.
• Cosmeceutical & Dermatological Research: Supports studies on the skin penetration and localized metabolism of salicylic acid in topical formulations.

Basic Information

Item	Details
Product Name	Salicylic Acid-Ring-Ul-14C
CAS No.	115918-62-2
Molecular Formula	C7H6O3 (with 14C label)
Molecular Weight	~138.12 g/mol (exact mass varies with isotopic enrichment)
Synonyms	2-Hydroxy[Ring-U-14C]benzoic Acid; [14C]Salicylic Acid; Radiolabeled Salicylic Acid; UL-14C Salicylic Acid; SA-14C; Benzoic acid, 2-hydroxy- (Ring-14C); Carbon-14 Labeled Salicylic Acid
EINECS	Contact for details

Quality Control

Every batch of Salicylic Acid-Ring-Ul-14C is produced and analyzed under strict quality control protocols to ensure identity, purity, and specific activity. Our quality commitment includes verification against internal reference standards and compliance with relevant guidelines for radiochemicals. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing parameters such as radiochemical purity, chemical purity, specific activity, and solvent content.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). For long-term storage, keep the container under an inert atmosphere such as argon or nitrogen in a dedicated, well-ventilated radioactive materials storage area.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Radiochemical Purity (HPLC)	≥ 98%
Chemical Purity (HPLC)	≥ 98%
Specific Activity	50-60 mCi/mmol (Contact for exact value)
Solvent (Residual)	< 2% (by NMR or GC)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.