Description

1,6-Diamino(Hexane-3,3,4,4-D4) is a deuterium-labeled derivative of 1,6-diaminohexane (hexamethylenediamine), where four hydrogen atoms are replaced with deuterium at the 3 and 4 positions of the carbon chain. This isotopic labeling makes it a crucial internal standard and tracer in analytical chemistry, particularly for mass spectrometry-based quantification, ensuring high accuracy and reliability in research data. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for metabolic studies, pharmacokinetics, and the development of novel deuterated compounds.

Application

• Internal Standard for Quantitative Analysis: Serves as a critical reference standard in LC-MS and GC-MS for the accurate quantification of hexamethylenediamine and related compounds in complex matrices.
• Metabolic Tracer Studies: Used in pharmaceutical and biochemical research to track metabolic pathways and drug distribution, leveraging the distinct mass signature of deuterium.
• Deuterated Compound Synthesis: Acts as a key building block for synthesizing more complex deuterium-labeled molecules for research in NMR spectroscopy and material science.
• Polymer Research: Employed in the development and study of specialized nylons and polyurethanes where isotopic labeling helps investigate polymerization mechanisms and material properties.
• Quality Control & Method Development: Essential for developing and validating robust analytical methods in compliance with regulatory standards (e.g., FDA, ICH) in industrial and academic laboratories.

Basic Information

Product Name	1,6-Diamino(Hexane-3,3,4,4-D4)
CAS No.	115797-53-0
Molecular Formula	C6H12D4N2
Molecular Weight	120.22 g/mol
Synonyms	Hexamethylenediamine-3,3,4,4-d4; 1,6-Hexanediamine-3,3,4,4-d4; 1,6-Diaminod4-hexane; Deuterated Hexamethylenediamine; 1,6-Diaminohexane-d4; HMD-d4; 1,6-Diamino-3,3,4,4-tetradeuterohexane; Bis(3-aminopropyl)ether-d4 (common misnomer)
EINECS	Contact for details

Quality Control

Our 1,6-Diamino(Hexane-3,3,4,4-D4) is produced under strict quality management systems. Each batch undergoes comprehensive analysis to ensure high chemical purity and isotopic enrichment, typically exceeding 98% chemical purity and 98 atom % D. Certificates of Analysis (COA) detailing specifications for assay, isotopic purity, and impurity profiles are provided and available upon request to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Isotopic Purity (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.