Description

1,6-Diamino(Hexane-2,2,5,5-D4) is a deuterium-labeled analog of 1,6-diaminohexane (hexamethylenediamine), a key building block in polymer chemistry. This isotopically labeled compound is essential for advanced research and development, providing a stable, non-radioactive tracer for mechanistic studies, metabolic pathway analysis, and as an internal standard in quantitative mass spectrometry. It is primarily utilized by researchers and process developers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise analytical tools and labeled intermediates.

Application

• Internal Standard for Analytical Chemistry: Used in quantitative LC-MS and GC-MS analysis for accurate measurement of hexamethylenediamine and related compounds in complex matrices.
• Metabolic Pathway Tracing: Serves as a deuterium-labeled tracer in pharmacological and biochemical research to study the absorption, distribution, metabolism, and excretion (ADME) of polyamide precursors.
• Polymer Science Research: Employed in the synthesis of deuterated nylons (e.g., Nylon-6,6) for studying polymer dynamics, morphology, and degradation mechanisms using techniques like NMR and neutron scattering.
• Pharmaceutical Intermediate: Acts as a labeled building block in the synthesis of deuterated active pharmaceutical ingredients (APIs) for improved metabolic stability and clinical research.
• Material Science Studies: Used to create labeled epoxy hardeners or other specialty polymers to investigate material properties and interfacial interactions.

Basic Information

Product Name	1,6-Diamino(Hexane-2,2,5,5-D4)
CAS No.	115797-51-8
Molecular Formula	C6H10D4N2
Molecular Weight	120.22 g/mol
Synonyms	Hexamethylenediamine-2,2,5,5-d4; 1,6-Hexanediamine-d4; 1,6-Diaminod4-hexane; Deuterated Hexamethylenediamine; H2N(CD2)4NH2; 1,6-Diaminohexane-d4; 1,6-Diaminoperdeuterohexane; HMDA-d4
EINECS	Contact for details

Quality Control

Our 1,6-Diamino(Hexane-2,2,5,5-D4) is produced under strict quality management systems. Each batch is characterized by NMR and mass spectrometry to confirm isotopic enrichment and chemical purity, ensuring consistency for sensitive research applications. Certificates of Analysis (COA) detailing assay, isotopic purity (D-enrichment), and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.