Description

1,6-Diamino(Hexane-1,1,6,6-D4) is a deuterated derivative of 1,6-diaminohexane (hexamethylenediamine), where four hydrogen atoms are replaced by deuterium, a stable hydrogen isotope. This isotopic labeling is critical for applications requiring precise molecular tracking and analysis, such as in advanced spectroscopy and metabolic studies. It is an essential building block for researchers and manufacturers in the fields of pharmaceutical development, analytical chemistry, and materials science who require high-purity, isotopically enriched compounds.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a quantitative reference standard in LC-MS and GC-MS analysis for accurate measurement of hexamethylenediamine and related compounds in complex matrices.
• NMR Spectroscopy Solvent & Reagent: Serves as a deuterated reagent or shift reference in Nuclear Magnetic Resonance (NMR) studies to elucidate molecular structure and dynamics without proton interference.
• Pharmaceutical Research & Drug Metabolism Studies (DMPK): Employed as a tracer to study the absorption, distribution, metabolism, and excretion (ADME) of drug candidates and biomolecules in vivo.
• Synthesis of Deuterated Polymers & Advanced Materials: A key monomer for producing deuterated nylons (e.g., Nylon-6,6) and other polyamides, which exhibit distinct physical properties for specialized optical and electronic applications.
• Biochemical & Mechanistic Probes: Utilized to investigate enzymatic pathways and reaction mechanisms where the fate of specific hydrogen atoms needs to be tracked.
• Organic Synthesis Intermediate: Acts as a deuterated linker or building block in the synthesis of complex labeled organic molecules, peptides, and dendrimers.

Basic Information

Product Name	1,6-Diamino(Hexane-1,1,6,6-D4)
CAS No.	115797-49-4
Molecular Formula	C6H12D4N2
Molecular Weight	120.23 g/mol
Synonyms	Hexamethylenediamine-1,1,6,6-d4; 1,6-Diaminohexane-d4; 1,6-Hexanediamine-d4; HMDA-d4; 1,6-Diaminoperdeuterohexane; 1,1,6,6-Tetradeutero-1,6-diaminohexane; 1,6-Diaminohexane (1,1,6,6-D4); Bis(3-aminopropyl)amine-d4 (related structure)
EINECS	Contact for details

Quality Control

Our deuterated chemicals are produced and handled under controlled conditions to ensure isotopic purity and chemical integrity. Each batch undergoes rigorous analytical testing, including NMR and Mass Spectrometry, to confirm deuterium enrichment levels and chemical purity. Certificates of Analysis (COA) detailing isotopic purity (e.g., D atom %), chemical purity, and relevant spectroscopic data are provided to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Isotopic Purity (D atom %)	≥ 98.0% (by NMR/MS)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.