Description

2-Benzoyl-1,2,3,4-Tetrahydro-Isoquinoline-3-Carboxylic Acid is a high-value, synthetically derived organic compound featuring a tetrahydroisoquinoline scaffold functionalized with benzoyl and carboxylic acid groups. This specific molecular architecture makes it a versatile and critical pharmaceutical intermediate and research chemical for advanced organic synthesis. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel bioactive molecules, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• Key Pharmaceutical Intermediate: Serves as a crucial building block in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold for designing and synthesizing new chemical entities (NCEs) for biological screening and structure-activity relationship (SAR) studies.
• Alkaloid Analog Synthesis: Employed in the preparation of synthetic analogs of natural isoquinoline alkaloids, which possess a wide range of pharmacological activities.
• Chemical Biology Probes: Utilized in the development of specialized molecular probes for studying enzyme interactions and biological pathways.
• Process Chemistry Development: Acts as a standard or intermediate in optimizing scalable and cost-effective synthetic routes for pilot and commercial-scale production.

Basic Information

Product Name	2-Benzoyl-1,2,3,4-Tetrahydro-Isoquinoline-3-Carboxylic Acid
CAS No.	115732-15-5
Molecular Formula	C17H15NO3
Molecular Weight	281.31 g/mol
Synonyms	2-Benzoyl-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid; 1,2,3,4-Tetrahydro-2-benzoyl-3-isoquinolinecarboxylic acid; 3-Carboxy-2-benzoyl-1,2,3,4-tetrahydroisoquinoline; BTHIQ-3-COOH; 2-Benzoyl-3-carboxy-1,2,3,4-tetrahydroisoquinoline
EINECS	Contact for details

Quality Control

Our production of 2-Benzoyl-1,2,3,4-Tetrahydro-Isoquinoline-3-Carboxylic Acid adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.