Description

6-Iodo-2,3-Dihydro-1H-Indole Hydrochloride is a versatile halogenated indoline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a functionalized indole core, enabling the construction of complex molecules for pharmaceutical and agrochemical research. This intermediate is essential for medicinal chemists and R&D professionals developing novel active ingredients, particularly in the areas of central nervous system (CNS) therapeutics and kinase inhibitors.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potent drug candidates targeting neurological disorders and oncology.
• Agrochemical Research: Used in developing novel pesticides and herbicides by acting as a core scaffold for bioactive molecules.
• Chemical Biology Probes: Serves as a starting material for creating labeled compounds and molecular probes for biochemical assays.
• Material Science: Potential monomer or functional unit in the synthesis of specialty polymers and advanced organic materials.
• Academic & Contract Research: Employed in university and CRO laboratories for method development and novel heterocyclic chemistry exploration.

Basic Information

Product Name	6-Iodo-2,3-Dihydro-1H-Indole Hydrochloride
CAS No.	115666-46-1
Molecular Formula	C8H9IN2•HCl
Molecular Weight	296.53 g/mol
Synonyms	6-Iodo-2,3-dihydro-1H-indole HCl; 6-Iodoindoline Hydrochloride; 1H-Indole, 6-iodo-2,3-dihydro-, hydrochloride; 2,3-Dihydro-6-iodo-1H-indole hydrochloride; 6-Iodoindoline hydrochloride salt; 115666-46-1; 6-Iodo-2,3-dihydroindole HCl
EINECS	Contact for details

Quality Control

Our 6-Iodo-2,3-Dihydro-1H-Indole Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.