Description

3-Hydroxy Detomidine Hydrochloride is a high-purity synthetic compound of significant interest in pharmaceutical research and development. This compound serves as a key intermediate or active metabolite in the synthesis and study of veterinary sedative and analgesic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of veterinary medicines. The material is supplied to meet the stringent quality requirements of advanced chemical synthesis and analytical applications.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of veterinary sedative drugs, particularly detomidine and its analogs.
• Metabolite Reference Standard: Used as an analytical standard in pharmacokinetic and metabolic studies for veterinary pharmaceuticals.
• Biochemical Research: Employed in research investigating α-2 adrenergic receptor agonists and their mechanisms of action.
• Veterinary Drug Development: Integral to the R&D pipeline for new sedative, analgesic, and anesthetic formulations for large animals.
• Quality Control & Testing: Serves as a certified reference material (CRM) for assay validation and impurity profiling in pharmaceutical quality control laboratories.

Basic Information

Product Name	3-Hydroxy Detomidine Hydrochloride
CAS No.	115664-37-4
Molecular Formula	C13H17ClN2O
Molecular Weight	252.74 g/mol
Synonyms	3-Hydroxydetomidine HCl; 4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole-5-methanol Hydrochloride; Detomidine Metabolite Hydrochloride; 3-OH-Detomidine HCl; 1H-Imidazole-5-methanol, 4-[1-(2,3-dimethylphenyl)ethyl]-, hydrochloride (1:1); (RS)-3-Hydroxydetomidine Hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Hydroxy Detomidine Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identity confirmation by IR and MS. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production standards. Specifications can be aligned with common pharmacopeial guidelines for reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.