Description

7-Indolinecarbonitrile is a versatile and high-value heterocyclic building block essential for advanced organic synthesis. Its unique indoline core fused with a reactive nitrile group makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new herbicides and insecticides, leveraging its heterocyclic scaffold.
• Material Science: Serves as a building block for specialty polymers and functional organic materials.
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to introduce the indoline moiety.
• Ligand and Catalyst Development: The nitrogen-rich structure is useful for creating novel chelating ligands in coordination chemistry.

Basic Information

Product Name	7-Indolinecarbonitrile
CAS No.	115661-82-0
Molecular Formula	C9H8N2
Molecular Weight	144.18 g/mol
Synonyms	7-Cyanoindoline; 1H-Indole-7-carbonitrile, 2,3-dihydro-; 2,3-Dihydro-1H-indole-7-carbonitrile; Indoline-7-carbonitrile; 7-CN-indoline
EINECS	Contact for details

Quality Control

Every batch of 7-Indolinecarbonitrile is produced and tested under a strict quality management system to ensure consistency and purity for research and development applications. Our standard grade meets high-purity specifications suitable for advanced synthetic chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive and should be handled under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.