Description

5,6,7,7A-Tetrahydrothieno[3,2-C]Pyridine-2(4H)-One Hydrochloride is a high-purity pharmaceutical intermediate and heterocyclic building block of significant commercial importance. Its value lies in its role as a key synthetic precursor in the development of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular therapies. This compound is essential for research and manufacturing organizations in the pharmaceutical, biotechnology, and fine chemical sectors seeking reliable, high-quality raw materials for complex synthesis.

Application

This versatile chemical intermediate is primarily utilized in advanced organic synthesis. Its specific applications include:

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates and established APIs.
• Chemical Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Fine Chemical Synthesis: Employed in the multi-step production of complex, high-value specialty chemicals.
• Academic Research: Serves as a substrate or reagent in university and institutional laboratories studying heterocyclic chemistry.
• Process Development & Scale-up: Used by process chemists to develop and optimize scalable manufacturing routes for target molecules.

Basic Information

Product Name	5,6,7,7A-Tetrahydrothieno[3,2-C]Pyridine-2(4H)-One Hydrochloride
CAS No.	115473-15-9
Molecular Formula	C7H10ClNOS
Molecular Weight	191.68 g/mol
Synonyms	2-Oxo-4,5,6,7-tetrahydrothieno[3,2-c]pyridine hydrochloride; 4,5,6,7-Tetrahydrothieno[3,2-c]pyridin-2(3H)-one hydrochloride; Thieno[3,2-c]pyridin-2(3H)-one, 4,5,6,7-tetrahydro-, hydrochloride; 2-Oxo-2,3,4,5,6,7-hexahydrothieno[3,2-c]pyridine hydrochloride
EINECS	Contact for details

Quality Control

Our production of 5,6,7,7A-Tetrahydrothieno[3,2-C]Pyridine-2(4H)-One Hydrochloride adheres to stringent quality management systems. All batches undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.