Description

1-Propanamine, 3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]- is a specialized organosilicon-protected amino alcohol intermediate, offering a unique combination of a reactive primary amine and a silyl-protected hydroxyl group. This compound is critical for synthetic chemists requiring selective protection and deprotection strategies in complex multi-step syntheses. It is primarily utilized in the research and development of advanced pharmaceuticals, agrochemicals, and sophisticated organic materials where precise molecular control is paramount.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological and metabolic pathways.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators that require specific chiral centers.
• Peptide Chemistry: Serves as a protected amino alcohol derivative for the solid-phase and solution-phase synthesis of modified peptides and peptidomimetics.
• Ligand and Catalyst Preparation: Employed in the development of chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Modification: Functional monomer for creating specialty polymers with amine and siloxane functionalities, enhancing material properties like adhesion and biocompatibility.
• Organic Synthesis Reagent: Facilitates complex multi-step organic transformations where temporary protection of the hydroxyl group is necessary.

Basic Information

Product Name	1-Propanamine, 3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-
CAS No.	115306-75-7
Molecular Formula	C9H23NOSi
Molecular Weight	189.37 g/mol
Synonyms	3-[(tert-Butyldimethylsilyl)oxy]-1-propanamine; 3-((tert-Butyldimethylsilyl)oxy)propan-1-amine; 3-(TBDMSO)propylamine; N/A-TBDMS-3-aminopropanol; 3-Aminopropyl tert-butyldimethylsilyl ether; TBDMS-protected 3-aminopropanol; O-(tert-Butyldimethylsilyl)-3-aminopropanol; 3-(Nonafluoro-tert-butyldimethylsiloxy)propylamine (related fluoride analog)
EINECS	Contact for details

Quality Control

Our production of 1-Propanamine, 3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]- adheres to stringent quality management protocols. Each batch is rigorously analyzed to ensure high chemical purity and consistency, meeting the exacting standards required for research and fine chemical synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is sensitive to fluoride/strong alkali conditions and moisture; ensure the container is kept tightly sealed to exclude atmospheric humidity. Keep away from incompatible materials such as strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.