Description

1H-Indole-2-Carboxamide,Octahydro-,[2S-(2-α-,3A-Bta-,7A-Bta-)]-(9Ci) is a high-purity, stereochemically defined indole derivative, serving as a critical chiral building block and synthetic intermediate for advanced pharmaceutical research and development. Its value lies in its complex, fused-ring structure which provides a versatile scaffold for constructing novel bioactive molecules, particularly in the areas of central nervous system (CNS) and metabolic disorder therapeutics. This compound is essential for medicinal chemists and process development scientists in pharmaceutical, biotechnology, and fine chemical industries who require precise, high-quality intermediates for drug discovery and API synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates targeting complex biological pathways.
• Medicinal Chemistry Research: Used as a core scaffold in structure-activity relationship (SAR) studies and lead optimization programs.
• Asymmetric Synthesis: Employed in the construction of complex, stereochemically rich molecules due to its defined [2S-(2-α-,3A-Bta-,7A-Bta-)] configuration.
• Neurological & CNS Drug Development: Investigated as a precursor for compounds interacting with neurotransmitter systems.
• Fine Chemical Production: Serves as a specialized intermediate in the multi-step synthesis of high-value agrochemicals and specialty chemicals.
• Academic & Contract Research: Utilized in university and CRO settings for exploratory synthetic chemistry and methodological development.

Basic Information

Product Name	1H-Indole-2-Carboxamide,Octahydro-,[2S-(2-α-,3A-Bta-,7A-Bta-)]-(9Ci)
CAS No.	115238-28-3
Molecular Formula	C11H18N2O
Molecular Weight	194.27 g/mol
Synonyms	Octahydro-1H-indole-2-carboxamide, (2S,3aS,7aS)-; (2S,3aS,7aS)-Octahydro-1H-indole-2-carboxamide; (2S,3aS,7aS)-Perhydroindole-2-carboxamide; (2S,3aS,7aS)-Hexahydro-1H-indole-2-carboxamide; (2S,3aS,7aS)-2-Carbamoyloctahydroindole; Stereoisomer of Octahydroindole-2-carboxamide; Chiral Indole Carboxamide Intermediate; 9CI Reference Compound
EINECS	Contact for details

Quality Control

Our 1H-Indole-2-Carboxamide,Octahydro-,[2S-(2-α-,3A-Bta-,7A-Bta-)]-(9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including chiral purity verification by HPLC, to confirm identity and meet stringent specifications. A comprehensive Certificate of Analysis (COA) detailing purity, chiral excess, and impurity profiles is provided with each batch to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.