Description

(R)-1-(n-Benzyloxycarbonylamino)Ethylphosphinic Acid is a high-purity chiral phosphinic acid derivative, serving as a critical building block in advanced organic synthesis. This compound is essential for the development of novel pharmaceuticals and agrochemicals, particularly where stereochemistry is a key factor for biological activity. It is primarily utilized by research institutions and industrial R&D departments focused on medicinal chemistry, asymmetric catalysis, and the synthesis of bioactive molecules.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of enzyme inhibitors, receptor antagonists, and other active pharmaceutical ingredients (APIs).
• Agrochemical Research: Building block for developing novel herbicides, fungicides, and plant growth regulators with enhanced stereoselective activity.
• Ligand Synthesis: Used in the preparation of chiral phosphine-phosphinite or phosphinic acid-based ligands for asymmetric catalysis.
• Peptidomimetics: Incorporated into peptide analogs to modulate stability, bioavailability, and receptor binding affinity.
• Chemical Biology Probes: Serves as a versatile handle for creating molecular probes to study biological pathways and enzyme functions.
• Material Science: Potential monomer or additive for specialty polymers where phosphorus-containing groups impart specific properties like flame retardancy or metal chelation.

Basic Information

Product Name	(R)-1-(n-Benzyloxycarbonylamino)Ethylphosphinic Acid
CAS No.	115115-40-7
Molecular Formula	C10H14NO4P
Molecular Weight	243.20 g/mol
Synonyms	(R)-1-[(Benzyloxycarbonyl)amino]ethylphosphinic Acid; (R)-N-Cbz-Aminoethylphosphinic Acid; (R)-1-(Cbz-Amino)ethylphosphonic Acid (common misnomer); (R)-1-Aminoethylphosphinic Acid, N-Cbz protected; Z-D-Ala(P)(OH) analog; (R)-N-(Benzyloxycarbonyl)-1-aminoethylphosphinic Acid; (R)-Cbz-AEP(O)(OH)H
EINECS	Contact for details

Quality Control

Our (R)-1-(n-Benzyloxycarbonylamino)Ethylphosphinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.