Description

4-(Trifluoromethyl)Cinnamamide is a high-value fluorinated organic intermediate characterized by its cinnamamide backbone and trifluoromethyl substituent. This compound is prized for its role in facilitating the synthesis of complex molecules, offering enhanced metabolic stability and lipophilicity to target structures. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting inflammation, oncology, and central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve biological activity and environmental persistence.
• Liquid Crystal & OLED Material Synthesis: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs), contributing to improved performance and stability.
• Polymer Modification: Incorporated as a specialty monomer to introduce fluorine into polymer chains, enhancing material properties such as chemical resistance, thermal stability, and surface characteristics.
• Chemical Biology & Proteomics: Employed as a probe or linker in bioconjugation chemistry and the study of protein-ligand interactions due to its reactive amide group.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting fundamental research in organic synthesis and fluorine chemistry.

Basic Information

Product Name	4-(Trifluoromethyl)Cinnamamide
CAS No.	115093-99-7
Molecular Formula	C10H8F3NO
Molecular Weight	215.17 g/mol
Synonyms	(E)-3-[4-(Trifluoromethyl)phenyl]prop-2-enamide; 4-(Trifluoromethyl)cinnamic acid amide; 3-(4-Trifluoromethylphenyl)acrylamide; (E)-3-(4-(Trifluoromethyl)phenyl)acrylamide; α,4-Bis(trifluoromethyl)benzeneacrylamide; Cinnamamide, 4-(trifluoromethyl)-; 2-Propenamide, 3-[4-(trifluoromethyl)phenyl]-, (2E)-
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethyl)Cinnamamide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing batch-specific results against our stringent specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.