Description

1H-Indole-5-Carboxylic Acid, 3-[4-(3,6-Dihydro-4-Phenyl-1(2H)-Pyridinyl)Butyl]-, Hydrochloride (1:1) is a high-purity, complex organic intermediate of significant interest in advanced pharmaceutical research and development. This compound is valued for its specific indole-based molecular architecture, which serves as a critical building block for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the discovery of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting central nervous system (CNS) disorders.
• Chemical Reference Standard: Used for analytical method development, validation, and quality control in pharmaceutical analysis.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization programs.
• Biochemical Research: Potential use in studying receptor-ligand interactions due to its specific heterocyclic structure.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CRMOs) for bespoke, multi-step synthetic routes.

Basic Information

Product Name	1H-Indole-5-Carboxylic Acid, 3-[4-(3,6-Dihydro-4-Phenyl-1(2H)-Pyridinyl)Butyl]-, Hydrochloride (1:1)
CAS No.	115092-85-8
Molecular Formula	C24H26N2O2·HCl
Molecular Weight	410.94 g/mol
Synonyms	3-[4-(3,6-Dihydro-4-phenyl-1(2H)-pyridinyl)butyl]-1H-indole-5-carboxylic acid hydrochloride; 3-[4-(3,6-Dihydro-4-phenyl-2H-pyridin-1-yl)butyl]-1H-indole-5-carboxylic acid hydrochloride; 115092-85-8; UNII-8V2Y8Q6W0P; 8V2Y8Q6W0P; CHEMBL3185142; SCHEMBL15450497; DTXSID701310145
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.2%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.