Description

7-(Chloromethyl)-2,2-Dimethyl-2,3-Dihydro-1-Benzofuran is a versatile and high-value organic intermediate characterized by its benzofuran core and reactive chloromethyl functional group. This compound matters for its role as a crucial building block in the synthesis of more complex molecules, enabling the introduction of the 2,2-dimethyl-2,3-dihydrobenzofuran moiety. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for constructing novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) or anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the dihydrobenzofuran scaffold can contribute to biological activity.
• Material Science Research: Serves as a precursor for functionalized polymers or organic electronic materials due to its aromatic structure and modifiable chloromethyl group.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for asymmetric catalysis or metal-organic frameworks (MOFs).
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	7-(Chloromethyl)-2,2-Dimethyl-2,3-Dihydro-1-Benzofuran
CAS No.	115070-62-7
Molecular Formula	C11H13ClO
Molecular Weight	196.67 g/mol
Synonyms	2,2-Dimethyl-7-(chloromethyl)-2,3-dihydro-1-benzofuran; 7-Chloromethyl-2,2-dimethyldihydrobenzofuran; 2,3-Dihydro-2,2-dimethyl-7-(chloromethyl)benzofuran; 2,2-Dimethyl-2,3-dihydrobenzofuran-7-ylmethyl chloride; Dihydrobenzofuran-7-methyl chloride; 115070-62-7; Benzofuran, 2,3-dihydro-7-(chloromethyl)-2,2-dimethyl-
EINECS	Contact for details

Quality Control

Our 7-(Chloromethyl)-2,2-Dimethyl-2,3-Dihydro-1-Benzofuran is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.