Description

Benzo[B]Thiophene-6-Carboxylic Acid, 2-Amino-3-(2-Chlorobenzoyl)-4,5,6,7-Tetrahydro-, Ethyl Ester is a high-purity, complex heterocyclic organic compound that serves as a critical advanced intermediate in pharmaceutical research and development. Its intricate molecular structure, featuring fused thiophene and tetrahydrobenzene rings with amino and chlorobenzoyl functional groups, makes it a valuable building block for synthesizing novel active pharmaceutical ingredients (APIs). This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries. It enables the exploration of new chemical entities with potential therapeutic applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and organic electronic materials.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process optimization for client projects.
• Academic Research: Used in university and institutional labs for methodological studies in organic synthesis and medicinal chemistry.

Basic Information

Product Name	Benzo[B]Thiophene-6-Carboxylic Acid, 2-Amino-3-(2-Chlorobenzoyl)-4,5,6,7-Tetrahydro-, Ethyl Ester
CAS No.	114777-87-6
Molecular Formula	C19H20ClNO3S
Molecular Weight	377.88 g/mol
Synonyms	Ethyl 2-Amino-3-(2-chlorobenzoyl)-4,5,6,7-tetrahydro-1-benzothiophene-6-carboxylate; 2-Amino-3-(2-chlorobenzoyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-6-carboxylic Acid Ethyl Ester; 6-Carbethoxy-2-amino-3-(2-chlorobenzoyl)-4,5,6,7-tetrahydrobenzo[b]thiophene; 114777-87-6; 2-Amino-3-(2-chlorobenzoyl)-4,5,6,7-tetrahydro-1-benzothiophene-6-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Benzo[B]Thiophene-6-Carboxylic Acid, 2-Amino-3-(2-Chlorobenzoyl)-4,5,6,7-Tetrahydro-, Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light sources to maintain stability and prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.