Description

7-Methylbicyclo[2.2.2]Oct-2-Ene-8-Carbonitrile is a specialized bicyclic nitrile compound that serves as a valuable and versatile synthetic intermediate in advanced organic chemistry. Its unique strained bicyclic structure and functional group combination make it a critical building block for constructing complex molecular architectures. This high-purity intermediate is essential for research and development in the pharmaceutical and agrochemical sectors, where it is used to create novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets, leveraging its rigid bicyclic scaffold.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where its structural complexity can contribute to unique modes of action.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with specific thermal or mechanical properties.
• Organic Synthesis Building Block: Employed in Diels-Alder reactions and other cycloadditions to construct complex polycyclic frameworks in academic and industrial R&D settings.
• Ligand and Catalyst Development: The nitrile group and olefin can be functionalized to create novel chiral ligands or organocatalysts for asymmetric synthesis.
• Fragrance and Flavor Chemistry: Potential intermediate for synthesizing unique musk or amber odorants due to its bicyclic, lipophilic character.

Basic Information

Product Name	7-Methylbicyclo[2.2.2]Oct-2-Ene-8-Carbonitrile
CAS No.	114718-69-3
Molecular Formula	C10H13N
Molecular Weight	147.22 g/mol
Synonyms	8-Cyano-7-methylbicyclo[2.2.2]oct-2-ene; 7-Methylbicyclo[2.2.2]oct-2-ene-8-carbonitrile; Bicyclo[2.2.2]oct-2-ene-8-carbonitrile, 7-methyl-; 2-Norbornene-8-carbonitrile, 1,7,7-trimethyl- (related structure); 7-Methyl-2,5-norbornadiene-8-carbonitrile (possible misnomer); 1-Aza-4-methyltricyclo[3.3.1.13,7]decane-2-carbonitrile (alternative systematic name); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 7-Methylbicyclo[2.2.2]Oct-2-Ene-8-Carbonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support custom synthesis and can tailor specifications, including chiral purity if required, to meet specific project needs. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Research Grade)
Purity (GC/HPLC)	≥ 99.0% (Premium Grade)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.