Description

Pemedolac CAS NO 114716-16-4 is a high-purity pharmaceutical intermediate and active ingredient. This compound is critical for the research and development of novel therapeutic agents, particularly in the field of non-steroidal anti-inflammatory drugs (NSAIDs). It is primarily utilized by pharmaceutical manufacturers, contract research organizations (CROs), and academic research institutions engaged in drug discovery and synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of advanced NSAID candidates and other bioactive molecules.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structure for developing new analgesic and anti-inflammatory drugs.
• Biochemical Research: Used in studies investigating cyclooxygenase (COX) enzyme inhibition mechanisms and structure-activity relationships (SAR).
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Preclinical Studies: Utilized in pharmacological and toxicological evaluations during early-stage drug development.

Basic Information

Product Name	Pemedolac
CAS No.	114716-16-4
Molecular Formula	C15H13NO3
Molecular Weight	255.27 g/mol
Synonyms	Pemedolac; 2-[4-(Methylthio)phenyl]-1H-indole-3-acetic acid; 2-[4-(Methylsulfanyl)phenyl]-1H-indole-3-acetic acid; 1H-Indole-3-acetic acid, 2-[4-(methylthio)phenyl]-; Pemedolacum; UNII-7J3YML7R4T; 7J3YML7R4T
EINECS	Contact for details

Quality Control

Our Pemedolac is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.